Origin paper
Efficacy of pre-operative diclofenac sodium in the control of post-endodontic pain
Double-blind randomized placebo-controlled clinical trial of efficacy of preoperative diclofenac sodium in the control of post-endodontic pain
Effect of pretreatment dexamethasone on postendodontic pain.
Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial.
The effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single‐centre randomized controlled trial
A Randomized Case-controlled Clinical Trial of the Effect of Preemptive Etoricoxib, Prednisolone and a Control Group on of Postoperative Sequelae after Surgical Removal of Impacted Mandibular Third Molars
Effect of supraperiosteal injection of dexamethasone on postoperative pain.
Consideration of steroids for endodontic pain
Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double‐blind Randomized Controlled Trial
Efficacy comparison of periapical infiltration injection of dexamethasone, morphine and placebo for postoperative endodontic pain.
Evidence-based recommendations for analgesic efficacy to treat pain of endodontic origin: A systematic review of randomized controlled trials.
Effect of variable doses of dexamethasone on posttreatment endodontic pain.
Management of Endodontic Pain: A Systematic Review of Randomized Controlled Trials
Nonsteroidal Anti‐inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta‐analysis
Effect of Dexamethasone Intraligamentary Injection on Post-Endodontic Pain in Patients with Symptomatic Irreversible Pulpitis: A Randomized Controlled Clinical Trial
Incidence of Postoperative Pain after Single- and Multi-Visit Endodontic Treatment in Teeth with Vital and Non-Vital Pulp
Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial.
LPG-sensing characteristics of nanocrystalline ZnFe2O4 synthesized by co-precipitation method
A Randomized Clinical Trial on Oral and Transdermal Diclofenac on Controlling Postoperative Endodontic Pain
Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.
Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion.
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Efficacy of Corticosteroids on Postoperative Endodontic Pain: A Systematic Review and Meta‐analysis
Effect of Corticosteroids on Pain Relief Following Root Canal Treatment: A Systematic Review
The effect of intramuscular injection of steroid on posttreatment endodontic pain.
Management of posttreatment endodontic pain with oral dexamethasone: a double-blind study.
A prospective randomized double-blind trial on efficacy of dexamethasone for endodontic interappointment pain in teeth with asymptomatic inflamed pulps.
CLINICAL STUDY OF EFFECT OF INFILTRATION INJECTION OF DEXAMETHASONE ON POST ENDODONTIC PAIN OF NECROTIC TEETH
Predictive models of pain following root canal treatment: a prospective clinical study.
Comparison of effect of intracanal use of ketorolac tromethamine and dexamethasone with oral ibuprofen on post treatment endodontic pain.
Evaluation of meloxicam (A cox-2 inhibitor) for management of postoperative endodontic pain: a double-blind placebo-controlled study.
Effect of Premedication with Anti-inflammatory Drugs on Post-Endodontic Pain: A Randomized Clinical Trial.
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.
Effect of Preoperative Corticosteroids in Patients with Symptomatic Pulpitis on Postoperative Pain after Single‐visit Root Canal Treatment: A Systematic Review and Meta‐analysis
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Postoperative pain in multiple-visit and single-visit root canal treatment.
Pharmacological Strategies to Control Post-operative Endodontic Pain
The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review.
The effect of pretreatment submucosal tramadol and dexamethasone injection on postendodontic pain in mandibular molar teeth with symptomatic irreversible pulpitis: A randomized controlled clinical trial.
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The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review.Predictive models of pain following root canal treatment: a prospective clinical study.Postoperative pain in multiple-visit and single-visit root canal treatment.Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.Incidence of Postoperative Pain after Single- and Multi-Visit Endodontic Treatment in Teeth with Vital and Non-Vital PulpEffect of pretreatment dexamethasone on postendodontic pain.Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.The effect of intramuscular injection of steroid on posttreatment endodontic pain.Nonsteroidal Anti‐inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta‐analysisEffect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion.Comparison of effect of intracanal use of ketorolac tromethamine and dexamethasone with oral ibuprofen on post treatment endodontic pain.Effect of variable doses of dexamethasone on posttreatment endodontic pain.Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial.Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.Management of posttreatment endodontic pain with oral dexamethasone: a double-blind study.Consideration of steroids for endodontic painA prospective randomized double-blind trial on efficacy of dexamethasone for endodontic interappointment pain in teeth with asymptomatic inflamed pulps.Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.Evaluation of meloxicam (A cox-2 inhibitor) for management of postoperative endodontic pain: a double-blind placebo-controlled study.Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.Effect of supraperiosteal injection of dexamethasone on postoperative pain.Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial.Evidence-based recommendations for analgesic efficacy to treat pain of endodontic origin: A systematic review of randomized controlled trials.Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double‐blind Randomized Controlled TrialEfficacy of Corticosteroids on Postoperative Endodontic Pain: A Systematic Review and Meta‐analysisEffect of Corticosteroids on Pain Relief Following Root Canal Treatment: A Systematic ReviewEfficacy comparison of periapical infiltration injection of dexamethasone, morphine and placebo for postoperative endodontic pain.Effect of Dexamethasone Intraligamentary Injection on Post-Endodontic Pain in Patients with Symptomatic Irreversible Pulpitis: A Randomized Controlled Clinical TrialEffect of Preoperative Corticosteroids in Patients with Symptomatic Pulpitis on Postoperative Pain after Single‐visit Root Canal Treatment: A Systematic Review and Meta‐analysisThe effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single‐centre randomized controlled trialThe effect of pretreatment submucosal tramadol and dexamethasone injection on postendodontic pain in mandibular molar teeth with symptomatic irreversible pulpitis: A randomized controlled clinical trial.Effect of Premedication with Anti-inflammatory Drugs on Post-Endodontic Pain: A Randomized Clinical Trial.Pharmacological Strategies to Control Post-operative Endodontic PainCLINICAL STUDY OF EFFECT OF INFILTRATION INJECTION OF DEXAMETHASONE ON POST ENDODONTIC PAIN OF NECROTIC TEETHLPG-sensing characteristics of nanocrystalline ZnFe2O4 synthesized by co-precipitation methodDouble-blind randomized placebo-controlled clinical trial of efficacy of preoperative diclofenac sodium in the control of post-endodontic painEfficacy of pre-operative diclofenac sodium in the control of post-endodontic painA Randomized Clinical Trial on Oral and Transdermal Diclofenac on Controlling Postoperative Endodontic PainA Randomized Case-controlled Clinical Trial of the Effect of Preemptive Etoricoxib, Prednisolone and a Control Group on of Postoperative Sequelae after Surgical Removal of Impacted Mandibular Third MolarsManagement of Endodontic Pain: A Systematic Review of Randomized Controlled TrialsSathorn, 2007Arias, 2013Mubarak, 2010Attar, 2008Ince, 2009Pochapski, 2009Gopikrishna, 2003Marshall, 1984Smith, 2017Parirokh, 2013Rogers, 1999Liesinger, 1993Parirokh, 2012Jalalzadeh, 2010Mehrvarzfar, 2012Krasner, 1986Marshall, 2002Glassman, 1989Gallatin, 2000Nekoofar, 2003Wells, 2011Mehrvarzfar, 2008Arslan, 2011Aminoshariae, 2016Praveen, 2017Shamszadeh, 2018Iranmanesh, 2017Shantiaee, 2012Mehrvarzfar, 2016Suneelkumar, 2018Elkhadem, 2018Aksoy, 2019Jorge-Araújo, 2018Mohammadi, 2008Saeed, 2014Chaudhari, 2016Kochhar, 2019Rasool, 2021Murugan, 2023Mubarak, 2021Ezmirly, 2019Sathorn, 2007Arias, 2013Mubarak, 2010Attar, 2008Ince, 2009Pochapski, 2009Gopikrishna, 2003Marshall, 1984Smith, 2017Parirokh, 2013Rogers, 1999Liesinger, 1993Parirokh, 2012Jalalzadeh, 2010Mehrvarzfar, 2012Krasner, 1986Marshall, 2002Glassman, 1989Gallatin, 2000Nekoofar, 2003Wells, 2011Mehrvarzfar, 2008Arslan, 2011Aminoshariae, 2016Praveen, 2017Shamszadeh, 2018Iranmanesh, 2017Shantiaee, 2012Mehrvarzfar, 2016Suneelkumar, 2018Elkhadem, 2018Aksoy, 2019Jorge-Araújo, 2018Mohammadi, 2008Saeed, 2014Chaudhari, 2016Kochhar, 2019Rasool, 2021Murugan, 2023Mubarak, 2021Ezmirly, 2019
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Introduction: The severity as well as the incidence of postoperative pain are associated with specific dental treatments, the highest being root canal therapy. The postoperative pain incidence has been reported to range from 3% to 58% after root canal treatment. The aim of the present study was to compare the efficacy of preoperative diclofenac sodium in the control of post-endodontic pain. Materials and Method: 120 patients were randomly selected and clinical examinations were conducted. The patients were randomly allocated using simple randomization technique into 2 experimental groups: Group 1, diclofenac sodium (VOVERON SR, 100 mg-oral) and Group 2, placebo (sucrose tablets). Both medications were administered 30 min before conventional root canal therapy. Patients were instructed to complete a pain diary; 6, 12, and 24 h after root canal instrumentation. The method used to measure clinical pain intensity was the visual analogue scale (VAS), which consisted of a 10 cm line anchored by two extremes, “no pain” and “pain as bad as it could be.” Thus, the pain intensity was assigned into four categorical scores: a) None (0); b) Mild (1-3); c) Moderate (4-6); and d) Severe (7-10). Results: Among the 120 volunteers who completed the study, 63.63% had mild pain and 36.37% had severe pain. Post endodontic pain showed a statistically significant difference between group 1 and group 2 at 6hr, 12hr and 24hr (P